Equipped with a highly effective drug bottle filling production line is the final stage of drug production process. For bottling, not only to achieve high-speed, accurate packaging of products, improve packaging efficiency, but also to meet the requirements of rapid production of multiple varieties ,Simple production line adjustment to achieve flexible production. This requires particular attention to the complete line design of the granule bottling line and the configuration of the single machine. This article intends to start from the design, manufacture, installation and debugging of the drug bottling production line for many years, and briefly introduces the current domestic advanced bottling production line, hoping to help the selection of the pharmaceutical production line.
The selection basis of drug bottling production line
When modern pharmaceutical companies deploy production lines, they often have to complete high-speed production of multiple products on one production line. Therefore, when designing a drug bottling line, it is first necessary to specify how many products need to be completed in this production line, and what processes are required for bottling each product.
Drug bottling processes generally include plastic bottle finishing, particle metering and bottling, crushing, moisture-proof items, plugging, capping or screw capping, aluminum foil sealing, and drug labeling. In addition, it can also realize some automated testing procedures, such as the detection of bottling volume, capping, sealing and labeling conditions, manuals and auto-cartoning of medicine bottles, and identification of corresponding product production information on medicines, instructions or packaging boxes. Wait.
The specifications of the vials, such as the shapes, diameters and heights of all bottles, the diameter and height of the bottle necks, which caps to use, the type and size of the drug labels used, are also the basis for the design. In addition, the specifications of the medicines to be packaged, including the specifications, shape and size of the medicines, and the amount of packaging for each bottle, must also be submitted at the same time. At the same time, we must also determine the speed and accuracy of the more appropriate production line.
Key equipment configuration
There are three key equipments for the drug bottling production line, the unscrambler, the metering and bottling machines, and the measuring bottling machine is the core equipment for the whole line.
There are two types of drug metering bottling: weighing and counting. Weighing and metering are mostly used for the packaging of liquids and powders. Weighing methods are also used when the weight of small particles or finished products has large deviations. At present, the most used automated particles. This article originated from the Chinese bottle network. Counting equipment for the photoelectric grain counting machine, the use of photoelectric induction principle of particle detection, counting. The drug particles are transported by multi-track multi-stage vibration, and the particles pass through the vibration transmission continuously and without passing through the photoelectric counting sensor to complete the counting of the particles. Due to the accurate counting, number of pellets and bottling speed, the photoelectric counting machine can be applied to many kinds of pharmaceutical particles. It can be widely used through the digital setting of the PLC control system to easily complete the variety replacement.
In addition to the photoelectric grain counting machine, early mechanical grain counting machines still have a great market through the modernization of modern automation and other advanced technologies. Compared with the photoelectric counting machine, the mechanical counting machine has certain advantages under the single product production conditions without frequent replacement of varieties, but it is far inferior to the photoelectricity in the accuracy of counting and rejecting the defective products. Equipment. At present, mechanical counting machines are more used for small-scale and less-automated small and medium-sized pharmaceutical companies.
The other two necessary equipment for several bottle filling lines are the bottle unscrambler and the capping machine. The basis for the selection of the unscrambler is mainly to satisfy the production speed of the counting machine. In addition, the bottle's appearance size also determines the selection of the unscrambler. The unscrambler on pharmaceutical packaging line generally has two structures, one is a two-wheel conveying structure automatic bottle-removing machine, and the bottle-keeping speed is 50 to 120 bottles/minute, which can meet the speed requirements of most bottle-feeding machines. Can be guaranteed; another model is a high-speed bottle unscrambler, the bottle speed can reach 250 bottles/minutes, and the structure is slightly complicated, which can meet the requirement of faster production cycle.
Similar to the unscrambler, the main basis for the selection of the capping machine is the production speed and the material, shape and size of the cap. From the structural point of view, there are linear and rotary capping machines, the production speed of up to 150 bottles / minute and 250 bottles / minute respectively, these two models can basically meet the speed requirements of the current number of lines. Different from the bottle unscrambler, due to the different types of caps, a variety of capping heads need to be prepared in order to replace the varieties and packaging methods.
Attachment equipment configuration
The bottle unscrambler, the pelletizer, and the capping machine are equipped with the necessary conveying equipment and basically form a simple number of packaging lines. In order to realize more automatic packaging functions, a number of auxiliary devices can be configured on the grain line, mainly in the following ways:
Inserting machine: Due to the intermittent movement, the filling equipment will not be too high. For the faster equipment, the maximum filling speed is 80 bottles/minute. If it exceeds this speed, it must be considered expensive. And need more space for continuous equipment, or parallel two to increase speed.
Electromagnetic induction sealing machine: electromagnetic induction foil sealing machine technology is relatively mature, basically all can meet the production speed requirements of 250 bottles / minute, it should be noted that in a long working situation, the device heat and affect the sealing effect. In addition, due to the use of an electromagnetic induction sealer for aluminum foil sealing, high-power magnetic fields not only interfere with the stable operation of other equipment, but also cause health hazards to operators who work long hours on the production line. Therefore, equipment that has passed EMC testing must be selected during equipment selection to ensure the stable operation of the equipment and the health of the production line operators.
Labeling machine: After completing the counting and packaging of medicines, several bottle bottling lines will also be equipped with labeling machines to achieve automatic labeling. Although there are various labeling positions in the current pharmaceutical packaging process, the labels used are generally pre-printed and roll-shaped adhesive labels. In addition, labeling machines that now meet the production speed requirement of more than 100 bottles per minute are required. Abound.
Cartoning machine: The automatic numbering line can also be equipped with a cartoning machine. The filled bottle can be loaded into the carton box along with the instructions to realize the full automation of the carton packaging. At present, the domestic production of cartoning machines can achieve a production speed of up to 80 boxes/minute. To achieve higher-speed production requirements, it is necessary to use an expensive continuous cartoning machine.
Whole line adjustment
After completing the complete line design of several bottled lines and selecting a reasonable stand-alone device, whether or not the design goal can be successfully achieved depends on the commissioning of the production line. The adjustment of automated production lines is mainly divided into software and hardware adjustments.
Adjust the position of the bottle on the entire conveyor system, the spacing between the guide bar and the bar, the detection and control points of the upper and lower processes, the conveyance of bottles and caps, etc. to ensure that the entire production line can basically be linked together, without major clogging defects, and then start to stand alone The equipment is precisely adjusted.
After ensuring that the entire line and stand-alone hardware are qualified for debugging, then according to different drug specifications and packaging methods, through the adjustment of the operating and control system parameters, all the varieties produced on-line are adjusted, and all parameters are stored. It is convenient to call later and shorten the time for changing the product.
It is hoped that the introduction of the above article can help the large number of pharmaceutical companies to configure an efficient pharmaceutical bottle-packing line. Of course, if companies encounter problems in selecting and configuring production lines, we are willing to give answers and help.