A recent study in the UK found that B. pertussis, which causes pertussis, has evolved at an extremely fast rate, which may be one of the reasons why such infectious diseases have spread rapidly around the world in recent years. However, experts stressed that existing vaccines can still provide effective protection for susceptible groups such as infants and young children, and timely vaccination is necessary.
Whooping cough is an acute respiratory infection, and the initial symptoms are similar to those of a cold. Patients can develop severe cough for more than two months, and infants are most susceptible to infection. According to data from the UK health department, the number of confirmed cases of pertussis in the UK in 2012 was nearly 10 times that of the previous year, and the number of cases of global infections also increased.
Researchers at institutions such as the University of Bath in the United States reported in the new issue of the Journal of Infectious Diseases in the United States that they studied the B. pertussis strains collected in the UK in 2012, focusing on the genetic coding of their surface proteins. It is through the identification of this protein that the vaccine triggers the body's immune response and allows the body to attack the germs.
The study found that the rate of evolution of this target protein is extremely rapid, making it easier for bacteria to "hide" the identification and attack of the immune system.
Researchers say that the rapid evolution of germs is likely to lead to new outbreaks, and it is necessary to adjust and improve existing vaccines. At the same time, they also pointed out that this study does not mean that the existing vaccine has expired, especially for the timely vaccination of susceptible populations such as pregnant women and children.
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