Japanese scientists found proteins that prevent brain cell death

Japanese scientists Tanako Tamaya and Ogawa recently discovered that there is a protein in human cells that can prevent brain cells from dying due to hypoxia. This discovery may be used to develop new treatments for cerebral vascular diseases such as cerebral thrombosis.

The two scientists published a paper in the March issue of "Natural Medicine" that said that under normal circumstances, this kind of protein called "ORP150" exists in human nerve cells and brain cells, but the number is not large. Scientists have conducted experiments with mice and found that in the case of induced cerebral thrombosis, mice that produce more of this protein in their bodies have suffered less brain damage than ordinary mice. When experimenting with human glial cells, it was also found that under hypoxic conditions, this protein continued to proliferate, and a large number of new glial cells were subsequently produced.

Patients with cerebrovascular diseases such as cerebral thrombosis will have massive death of brain cells due to blocked blood flow and insufficient supply of oxygen and nutrients. Even if rescued, sometimes serious sequelae will remain. The two scientists believe that if we can find a way to multiply "ORP150", we can effectively reduce the symptoms of patients with cerebrovascular diseases such as cerebral thrombosis.

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