They performed maxillary replacement surgery on a 65-year-old patient, using stem cells isolated from his own adipose tissue for incubation, and then placed into a bone graft grown in his abdomen. This breakthrough achievement has opened up a new path for the treatment of severe tissue damage and is expected to make customized human living parts faster a reality.
According to Reuters, Rita Suroning, who is engaged in regenerative medicine research at the University of Tampere, said: "There have been some similar methods before, but those are not using the patient's own stem cells and cultured to differentiate into bone tissue. "Su Luoning said that the patient is recovering very quickly. If he receives a leg bone transplant, the recovery rate will definitely not be as good as now.
She also said that the medical team did not use animal tissue, thereby eliminating the risk of infection with viruses that may be hidden in the DNA of the animal, which also complied with the relevant EU requirements. Transplants made with the patient's own stem cells will not cause rejection. Su Luoning and her colleagues isolated stem cells from patients' fat and placed them in a nutrient solution containing patient serum for two weeks of culture. After that, they extracted immature cells that could produce bones, muscles and blood vessels.
After collecting a sufficient number of cells, they attached these cells to a scaffold made of calcium phosphate biomaterial and placed them in the patient's abdomen for 9 months. As a result, these cells became a variety of tissues and even generated blood vessels. The doctors then transplanted and fixed the generated piece to the patient's face, and connected the blood vessels with the blood vessels in the neck through microsurgery.
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